HILO WAVE and RE2O — not sure what the difference is? At BE THE NEW CLINIC in Gangnam, we’ve put together an honest breakdown of which skin booster suits which type of sunken cheek concern.
Today, we’re breaking down HILO WAVE and RE2O: what makes them different, and which one might be the better fit for your skin — based on your individual assessment rather than a one-size-fits-all approach.
More People Visiting Korea for Aesthetic Treatments Are Searching for Answers About Sunken Cheeks
Lately, more and more people planning a trip to Korea are combining their travel with a visit to a Korea aesthetic clinic. And one of the most common concerns we hear? It sounds exactly like this:
“My cheeks look so hollow, and my whole face looks flat. I’m scared of fillers. Is there a more natural option?”
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At BE THE NEW CLINIC in Gangnam, Seoul, this is one of the most common concerns we hear — and our specialists are here to help you find the right answer.
HILO WAVE vs RE2O vs Juvelook Volume — Quick Comparison

These three have become the most talked-about collagen boosters in Korea since 2025. Here’s a simple side-by-side:
| HILO WAVE | RE2O | Juvelook Volume | |
|---|---|---|---|
| Key Ingredient | DUAL-HA | Dermal components (ECM booster) | Collagen stimulator |
| Main Effect | Stimulates collagen and elastin; improves volume, hydration, and elasticity together | Rebuilds skin density; smooths fine lines and texture | Natural, gradual volume restoration |
| Best For | Mid-face volume + overall skin quality improvement | Loose skin texture, enlarged pores, fine lines | Deep hollowness, nasolabial folds, volume loss |
| Results Timeline | Relatively fast results with long-term skin improvement | Smoother skin texture over time | Gradual improvement, minimal visible downtime |
Because the right solution depends on your skin condition and the area of concern, it’s important to understand what each treatment actually does before choosing.
What Are HILO WAVE and RE2O, Exactly?
HILO WAVE — Collagen Booster & Bio-Stimulator

HILO WAVE isn’t just a hydration shot. It’s a bio-stimulator powered by DUAL-HA that actively encourages your skin to produce its own collagen and elastin, firming from the inside while creating a visible glow on the surface. Think of it as improving both how your skin feels and how it looks, at the same time.
HOW IT FEELS
✓Skin concerns visibly addressed over time
✓Collagen and elastin are boosted
✓Skin becomes firmer and lifted
HOW IT LOOKS
✓Faster visible results
✓Hyaluronic acid boost + glass skin effect
✓Added volume
If you’re dealing with cheek volume loss alongside overall skin quality concerns, HILO WAVE could be a good fit for you.
RE2O — Dermal Density Booster

RE2O is a skin booster based on dermal ECM components that help rebuild the structural density of your skin. It helps refine pores, smooth fine lines, and improve overall skin texture — so the cheeks look firmer and more defined from the outside in. It’s particularly well-suited for those whose skin feels thinner and less elastic, or whose facial bone structure has become more pronounced due to reduced skin thickness.
Why Do HILO WAVE and RE2O Take Different Approaches to Cheek Volume Loss?
Sunken cheeks don’t always have a single cause. The issue could be:
✓Loss of volume and elasticity within the skin layers
✓Thinning of the dermis, leading to reduced skin density
✓A combination of both at the same time
Even if two people search for the same sunken cheeks Korea treatment, the right approach can look completely different depending on the root cause. At BE THE NEW CLINIC in Gangnam, Dr. Tae Young Jung — with over 20 years of clinical experience — personally assesses each patient’s skin before recommending a treatment plan tailored specifically to them.
Who Should Consider HILO WAVE?
HILO WAVE may be a good fit if you:
✓Want to naturally restore volume in the mid-face area
✓Looking for minimal downtime with relatively fast, visible results
✓Want to improve overall skin quality — elasticity, hydration, and volume
✓Struggling with internal skin dryness
✓Want a treatment with a low risk of side effects
HILO WAVE fills the skin from within, and results can be further enhanced depending on the treated area and dosage.
Who Should Consider RE2O?
RE2O may be a better fit if you:
✓Feel like your skin has become thinner and less firm over time
✓Are bothered by enlarged pores or fine lines
✓Notice that hollowed cheeks are making your facial bone structure more prominent
✓Want to focus on skin density and texture before addressing volume
RE2O works by strengthening the internal structure of your skin tissue, making the dermis firmer and more compact — as a result, sunken cheeks naturally appear more refined and defined.
Can HILO WAVE and RE2O Be Done Together?
Skin rarely comes with just one concern. Many patients experience a combination of reduced elasticity, dull or uneven texture, and hollowness at the same time. In those cases, a skilled clinician may recommend planning both treatments together.
At Be The New Clinic, rather than trying to do everything at once, we help you prioritize based on your current skin condition and build a step-by-step treatment plan. Our staff includes English-speaking team members, so feel free to reach out and book a consultation that fits around your Korea travel schedule.
HILO WAVE vs RE2O — Frequently Asked Questions
|
Q. Is HILO WAVE different from a filler? |
Yes, they’re quite different. HILO WAVE is a DUAL-HA bio-stimulator that encourages your skin to produce collagen and elastin on its own. Unlike a filler, which physically adds structure and volume, HILO WAVE stimulates your skin’s natural regeneration process for results that look and feel more natural. |
|
Q. How long do RE2O results last? |
Improvements in dermal density tend to develop gradually over several months and are generally well-maintained. The exact duration varies from person to person, so we’d recommend discussing your expectations with a clinician during consultation. |
|
Q. Can I get these treatments during a trip to Korea? |
Both treatments involve relatively short recovery periods. That said, individual responses can vary, so we recommend avoiding any important plans the day after your procedure, just to be safe. |
|
Q. Which should I do first — HILO WAVE or RE2O? |
This depends on your current skin concerns and should be determined through a proper clinical assessment. Our specialists at Be The New Clinic will guide you through the best order based on your individual skin condition. |
Book a Consultation at Be The New Clinic in Seoul
When it comes to sunken cheeks, the treatment name matters less than understanding what your skin actually needs right now. Dr. Tae Young Jung at Be The New Clinic brings over 20 years of hands-on experience to every patient diagnosis — no generic plans, just a personalized approach built around you.
Thinking about booking before your trip to Korea? Reach out anytime. We’d love to help you plan.
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⛓️ How to Find Be The New Clinic
5–10 minutes on foot from Apgujeong Station (Line 3), Exit 4
4th and 5th floor, Be The New Building, 9 Nonhyeon-ro 155-gil, Gangnam-gu, Seoul (564-4, Sinsa-dong)
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Be careful of side effects such as bleeding, infection, and asymmetry after surgery.
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